按照日本药典规定的液相色谱法,用YMC-Triart C18 ExRS Plus色谱柱(规格:4.6*150mm,5um,8nm)测定奥美沙坦酯片的含量,分离度及相对标准偏差完全符合规定。
HHPLCDATASHEET*Standard solution was prepared from Olmesartan medoxomil supplied as a reagent for laboratory use.nt com. cn 才儿头廿儿夕>下卜少三儿锭(日本薬局方記載条件)Olmesartan Medoxomil Tablets (The Japanese Pharmacopoeia)F150113J Standard solution*(0.04 mg/mL Olmesartan medoxomil, 0.01 mg/mL p-Hydroxybenzoic acid isobutyl ester) Column : Triart C18 ExRS plus (5 pm,8 nm) 150 X4.6mml.D. Eluent : phosphate buffer (pH 3.4)*/acetonitrile (33/17) Dissolve 2.04 g of KH2PO; in 1000 mL water, adjust pH to 3.4 with a solution of *2 1.73 g of phosphoric acid in 1000 mL water Flow rate : 1.2 mL/min (adjust the flow rate so that the retention time of olmesartan medoxomil is about 16 min Temperature :40℃ Detection : UV at 250 nm Injection : 10 pL (The Japanese Pharmacopoeia 16th 2nd supplement; Assay) 色谱条件及系统适应性结果见谱图
还剩1页未读,是否继续阅读?
深圳凯米斯科技有限公司为您提供《奥美沙坦酯片中奥美沙坦酯含量检测方案(液相色谱柱)》,该方案主要用于化药制剂中含量测定检测,参考标准--,《奥美沙坦酯片中奥美沙坦酯含量检测方案(液相色谱柱)》用到的仪器有