脑动脉瘤中流体力学特性的影响研究检测方案(粒子图像测速)

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检测样品: 癌细胞/肿瘤细胞
检测项目: 流体力学特性的影响研究
浏览次数: 571
发布时间: 2012-07-30
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北京欧兰科技发展有限公司

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Embolic coiling is the most popular endovascular treatment available for cerebral aneurysms. Nevertheless, the embolic coiling of wide-neck aneurysms is challenging and, in many cases, ineffective. Use of highly porous stents to support coiling of wide-neck aneurysms has become a common procedure in recent years. Several studies have also demonstrated that high porosity stents alone can significantly alter aneurysmal hemodynamics, but differences among different stent configurations have not been fully characterized. As a result, it is usually unclear which stent configuration is optimal for treatment. In this paper, we present a flow study that elucidates the influence of stent configuration on cerebral aneurysm fluid dynamics in an idealized wide-neck basilar tip aneurysm model. Aneurysmal fluid dynamics for three different stent configurations (half-Y, Y and, cross-bar) were first quantified using particle image velocimetry and then compared. Computational fluid dynamics (CFD) simulations were also conducted for selected stent configurations to facilitate validation and provide more detailed characterizations of the fluid dynamics promoted by different stent configurations. In vitro results showed that the Y stent configuration reduced cross-neck flow most significantly, while the cross-bar configuration reduced velocity magnitudes within the aneurysmal sac most significantly. The half-Y configuration led to increased velocity magnitudes within the aneurysmal sac at high parent-vessel flow rates. Experimental results were in strong agreement with CFD simulations. Simulated results indicated that differences in fluid dynamic performance among the different stent configurations can be attributed primarily to protruding struts within the bifurcation region.

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北京欧兰科技发展有限公司为您提供《脑动脉瘤中流体力学特性的影响研究检测方案(粒子图像测速)》,该方案主要用于癌细胞/肿瘤细胞中流体力学特性的影响研究检测,参考标准--,《脑动脉瘤中流体力学特性的影响研究检测方案(粒子图像测速)》用到的仪器有德国LaVision PIV/PLIF粒子成像测速场仪、三维立体PIV