血小板,双瓣尖人工心脏瓣膜,凝血趋势,新型体外流动系统中流场速度场,速度矢量场检测方案(粒子图像测速)

Thromboembolic events caused by implanted cardiovascular devices present serious challenges to surgeons and researchers alike. In particular bileaflet mechanical heart valves are prone to thrombus formation in the hinge region due to a combination of high shear stress and stagnation regions. Shear-induced platelet activation and aggregation is usually studied using viscometers, parallel plate flow, and other non-physiologic in vitro configurations. However, it is desirable to study this phenomenon in a more physiological environment.