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Concern about the impact on public health from potentially toxic elements and compounds present in everyday foodstuff has led to new legislative guidance. The inorganic forms of arsenic (As) are known to be toxic and carcinogenic to humans, and food and drink are a potential source of exposure [1]. To reduce the intake of inorganic arsenic from the diet, the U.S. Food and Drug Administration (FDA) proposed a new action level for inorganic arsenic in apple juice of 10 μg/L in 2013 [2,3]. Also, following the eighth meeting of the CODEX Committee on Contaminants in Food, the World Health Organization (WHO) proposed a guideline for inorganic As in polished rice of 0.2 mg/kg [4]. There is a clear need for reliable screening methods to accurately determine the levels of such contaminants in food and drink products. The detection limits required are low, as a 0.2 mg/kg limit equates to a digestate concentration of 2 μg/L (assuming a 100x digestion dilution). Even small errors in the precision and accuracy of the analytical method could result in a food product being wrongly classified as safe. Selenium (Se) is an essential micronutrient that can be deficient in the diet as Se-poor soils yield Se-poor food crops. Accurate quantification of Se in food is necessary to assess nutrient status.
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Accurate and Sensitive Analysis ofArsenic and Selenium in Foods Use the Agilent 8800 Triple Quadrupole ICP-QQQ toremove doubly charged REE interferences Introduction： Concern about the impact on public health from potentially toxic elements and compounds presentin everyday foodstuff has led to new legislative guidance. The inorganic forms of arsenic (As) areknown to be toxic and carcinogenic to humans， and food and drink are a potential source ofexposure [1]. To reduce the intake of inorganic arsenic from the diet， the U.S. Food and DrugAdministration (FDA) proposed a new action level for inorganic arsenic in apple juice of 10 ug/L in2013 [2，3]. Also， following the eighth meeting of the CODEX Committee on Contaminants in Food，the World Health Organization (WHO) proposed a guideline for inorganic As in polished rice of 0.2mg/kg [4]. There is a clear need for reliable screening methods to accurately determine the levels ofsuch contaminants in food and drink products. The detection limits required are low， as a 0.2 mg/kglimit equates to a digestate concentration of 2 ug/L (assuming a 100x digestion dilution). Even smallerrors in the precision and accuracy of the analytical method could result in a food product beingwrongly classified as safe. Selenium (Se) is an essential micronutrient that can be deficient in thediet as Se-poor soils yield Se-poor food crops. Accurate quantification of Se in food is necessary toassess nutrient status. Agilent Technologies
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