别称
Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL
宿主
Rabbit
适应种属
Human, Mouse, Rat
亚型
IgG
验证应用
ELISA, WB, IHC, IF, FC
产品信息
产品名称
anti- Adenylosuccinate lyase antibody
货号
QSab00161
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
宿主
Rabbit
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
背景介绍
ADSL (adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate (PMID:18524658) . Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency) . In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features (PMID:20884265) ..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation (PMID:9545543) . It has 2 isoforms produced by alternative splicing.
免疫原信息
免疫原
adenylosuccinate lyase
别称
Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL
分子量
55 kDa
应用
验证应用
ELISA, WB, IHC, IF, FC
建议稀释比例
WB :1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
更多
企业名称
上海钦胜生物科技有限公司
企业信息已认证
企业类型
信用代码
27000000202008180010
成立日期
2020-08-18
注册资本
100
经营范围
从事生物科技、医疗科技领域内的技术开发、技术咨询、技术转让;仪器仪表、机电设备、机械设备、玻璃制品、电子产品、医疗器械、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品)的销售。 【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海钦胜生物科技有限公司
公司地址
上海市松江区余山镇陶干路701号5幢
客服电话