别称
MBP, Myelin A1 protein, Myelin basic protein
宿主
Rabbit
适应种属
Human, Mouse, Rat
亚型
IgG
验证应用
ELISA, WB, IHC, IF
产品信息
产品名称
anti- Myelin basic protein antibody
货号
QSab05465
规格
100μg
状态
liquid
纯化方法
Immunogen affinity purified
纯度
≥95% as determined by SDS-PAGE
宿主
Rabbit
克隆性
polyclonal
亚型
IgG
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
背景介绍
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
免疫原信息
免疫原
myelin basic protein
别称
MBP, Myelin A1 protein, Myelin basic protein
分子量
34 kDa
应用
验证应用
ELISA, WB, IHC, IF
建议稀释比例
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
更多
企业名称
上海钦胜生物科技有限公司
企业信息已认证
企业类型
信用代码
27000000202008180010
成立日期
2020-08-18
注册资本
100
经营范围
从事生物科技、医疗科技领域内的技术开发、技术咨询、技术转让;仪器仪表、机电设备、机械设备、玻璃制品、电子产品、医疗器械、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品)的销售。 【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海钦胜生物科技有限公司
公司地址
上海市松江区余山镇陶干路701号5幢
客服电话