anti- MMACHC antibody

 宿主

Rabbit

 适应种属

Human, Mouse, Rat

 亚型

IgG

 验证应用

ELISA, WB

产品信息

产品名称

anti- MMACHC antibody

货号

QSab05227

规格

100μg

状态

liquid

纯化方法

Immunogen affinity purified

纯度

≥95% as determined by SDS-PAGE

宿主

Rabbit

克隆性

polyclonal

亚型

IgG

存储

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

背景介绍

Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate(PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin(PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen(PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives(PubMed:21071249).

免疫原信息

免疫原

methylmalonic aciduria(cobalamin deficiency) cblC type, with homocystinuria

分子量

32 kDa

应用

验证应用

ELISA, WB

建议稀释比例

WB: 1:500-1:2000