别称
Antithrombin, Antithrombin III, AT3, ATIII, HEPARIN COFACTOR I, Serpin C1, SERPINC1
宿主
Mouse
适应种属
Human, Mouse, Rat
亚型
IgG1
验证应用
ELISA, WB
产品信息
产品名称
anti- Antithrombin III antibody
货号
QSab00449
规格
100μg
状态
liquid
纯化方法
Protein A+G purification
纯度
≥95% as determined by SDS-PAGE
宿主
Mouse
克隆性
monoclonal
亚型
IgG1
存储
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
背景介绍
SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
免疫原信息
免疫原
serpin peptidase inhibitor, clade C (antithrombin) , member 1
别称
Antithrombin, Antithrombin III, AT3, ATIII, HEPARIN COFACTOR I, Serpin C1, SERPINC1
分子量
53 kDa
应用
验证应用
ELISA, WB
建议稀释比例
WB :1:500-1:5000