anti- alpha 1 Antichymotrypsin/AACT antibody

 别称

A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3

 宿主

Mouse

 适应种属

Human

 亚型

IgG2b

 验证应用

ELISA, WB, IHC

产品信息

产品名称

anti- alpha 1 Antichymotrypsin / AACT antibody

货号

QSab00318

规格

100μg

状态

liquid

纯化方法

Protein A+G purification

纯度

≥95% as determined by SDS-PAGE

宿主

Mouse

克隆性

monoclonal

亚型

IgG2b

存储

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

背景介绍

Human SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease(COPD), Parkinson’s disease(PD), Alzheimer’s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.

免疫原信息

免疫原

serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3

别称

A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3

分子量

60 kDa

应用

验证应用

ELISA, WB, IHC

建议稀释比例

WB: 1:1000-1:10000; IHC: 1:20-1:300