anti- AHR antibody

别称

Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76

 宿主

Rabbit

 适应种属

Human, Mouse

 亚型

IgG

 验证应用

ELISA, WB, IHC, IP

产品信息

产品名称

anti- AHR antibody

货号

QSab00231

规格

100μg

状态

liquid

纯化方法

Immunogen affinity purified

纯度

≥95% as determined by SDS-PAGE

宿主

Rabbit

克隆性

polyclonal

亚型

IgG

存储

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

背景介绍

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

免疫原信息

免疫原

aryl hydrocarbon receptor

别称

Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76

分子量

105 kDa

应用

验证应用

ELISA, WB, IHC, IP

建议稀释比例

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200