重组人5T4蛋白|5T4蛋白|重组人滋养层糖蛋白

产品编号: KMP2244

产品名称: Human 5T4 Protein, Avi Tag, His Tag

中文名称: 重组人5T4蛋白

中文全称: 重组人滋养层糖蛋白

关键词: 滋养层糖蛋白, 5T4 Protein, Human 5T4AG Protein, Human M6P1 Protein, Human WAIF1 Protein, Human, Human 5T4 Protein, Avi Tag, His Tag, Recombinant Protein, KMP2244

物种: Human

宿主: HEK293 Cells

规格: 50ug, 100ug, 200ug

纯化方式: Affinity purification

纯度: >95% as determined by SDS-PAGE

内毒素水平: <1.0 EU/ug determined by the LAL method

缓冲体系: PBS, pH7.4

Uniprot: Q13641#structure

SDS-PAGE: KMP2244 SDS-PAGE image1.pnga

功能: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.

产品背景: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.

运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

说明: This product is for research use only.

官网链接: https://www.kmdbioscience.cn/

参考文献: 1 Dev. Cell 21:1129-1143 (2011)