Quinapril hydrochloride

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抑制剂描述：

产品名称：Quinapril hydrochloride

产品别名：见爱必信官网

英文别名：Quinapril hydrochloride

靶点：ACE

CAS：82586-55-8

纯度：>98%

外观：见爱必信官网

保存方法：-20°C

描述：

Quinapril hydrochloride (Accupril) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM. Quinapril hydrochloride (Accupril) used in the treatment of hypertension and congestive heart failure. Quinapril is a prodrug. Quinapril is converted to its active metabolite, quinaprilat, in the liver. Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor, angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms. Due to reduced angiotensin production, plasma concentrations of aldosterone are also reduced, resulting in increased excretion of sodium in the urine and increased concentrations of potassium in the blood.

溶解性：Ethanol ：88 mg/mL (185.3 mM)
DMSO ：15 mg/mL (31.6 mM)
Water ：87 mg/mL (183.2 mM)

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