分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）

英文名称    SMOC2    

中文名称    分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）    

别    名    Secreted modular calcium binding protein 2; SMAP 2; SMAP2; SMOC 2; Smooth muscle associated protein 2; SPARC related modular calcium binding 2; dJ421D16.1; MST117; MSTP117; bA270C4A.1; bA37D8.1; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein); MSTP140; SMOC2_HUMAN.    

分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）     

说 明 书    0.1ml  0.2ml      

研究领域    心血管  细胞生物  信号转导  生长因子和激素  转录调节因子  血管内皮细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    47kDa    

细胞定位    细胞膜 细胞外基质 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SMOC2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）产品介绍    background:
SMOC 2 (Secreted modular calcium binding protein 2) is a secreted modular protein containing an EF hand calcium binding domain homologous to that in BM40. It consists of two thyroglobulin like domains, a follistatin like domain and a novel domain found only in the homologous SMOC 1. SMOC 1 and 2 form a separate group within the BM40 family. SMOC 2 is a glycoprotein with a calcium dependent conformation. SMOC 2 contains 2 EF hand calcium binding domains, 1 Kazal like domain and 2 thyroglobulin type I domains.

Function:
Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. 

Subunit:
Binds various proteins from the extracellular matrix (By similarity). 

Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane (By similarity). 

DISEASE:
Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1) [MIM:125400]. A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 

Similarity:
Contains 2 EF-hand domains. 
Contains 1 Kazal-like domain. 
Contains 2 thyroglobulin type-1 domains. 

Database links:
UniProtKB/Swiss-Prot: Q9H3U7.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）

hz-8151R FAM36A  FAM36A蛋白抗体

hz-8152R FAM50A  FAM50A蛋白抗体

hz-8153R FAM134C  FAM134C蛋白抗体

hz-8154R Histone H2A.Z/ H2AFZ  组蛋白H2AZ抗体

hz-8155R GM130  高尔基体自身蛋白GM130抗体

hz-8156R FBRSL1  乙型肝炎病毒X蛋白反转录蛋白9抗体

hz-8157R GMRP1/BTBD10  糖代谢相关蛋白1抗体

hz-8158R BTBD1/HCV NS5A transactivated protein 8  丙肝病毒NS5A反转录蛋白8抗体

hz-8159R BTBD6  BTBD6蛋白抗体

hz-2282R PPO  腺样癌特异性相关抗原PPO抗体

hz-8160R G protein alpha  G蛋白α抗体

hz-8161R G protein beta subunit like  G蛋白β样蛋白抗体

hz-8162R CHD3  ATP依赖的解旋酶CHD3抗体

hz-8163R WDR79/TCAB1  端粒酶卡哈尔体蛋白抗体

hz-8164R TBL1Y  转导β样蛋白1抗体

hz-8165R RB1CC1  RB1的诱导卷曲蛋白RB1CC1抗体

hz-8166R COX5A  细胞色素c氧化酶5A抗体

hz-8167R CHCHD6  卷曲螺旋结构域蛋白CHCHD6抗体

hz-8168R GTF2B  通用转录因子GTF2B抗体

hz-8169R CBX1/HP1 β  异染色体同源蛋白1抗体

hz-8170R KMT3B/NSD1/ARA267  组蛋白甲基化KMT3B抗体（雄激素受体激活蛋白）

hz-8171R NFIC  核因子1C型抗体

hz-8172R IKAROS  锌指蛋白IKAROS抗体

hz-8173R Dbx2  大脑发育同源蛋白2抗体

hz-8174R HLX1  同源异型盒基因HLX1蛋白抗体

hz-8175R GTF2H1  通用转录因子2H肽1抗体

hz-8176R PHF8  组蛋白赖氨酸去甲基化酶PHF8抗体

hz-8177R KIF11/Eg5/TRIP5  驱动蛋白样蛋白1抗体（甲状腺激素受体相互作用蛋白5）

hz-8178R KDM5C/Jarid1C/SMCX  组蛋白去甲基化Jarid1C抗体

hz-8179R phospho-Eg5(Tyr92)  磷酸化驱动蛋白样蛋白1抗体

hz-8180R COMMD9  铜代谢结构域蛋白9抗体