β淀粉样蛋白前体蛋白结合蛋白2抗体

供货周期： 7天

品牌：

型号： 0.2ml/200μg

货号：

报价： ¥1

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产品介绍

β淀粉样蛋白前体蛋白结合蛋白2抗体勿使用无霜冷冻箱，因为会冷冻循环，这样会损伤抗体。

英文名称 Anti-APPBP2

中文名称 β淀粉样蛋白前体蛋白结合蛋白2抗体

别名 amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish

产品类型一抗

β淀粉样蛋白前体蛋白结合蛋白2抗体研究领域免疫学神经生物学 Alzheimer's

蛋白分子量 predicted molecular weight: 67kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human APPBP2

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

β淀粉样蛋白前体蛋白结合蛋白2抗体产品介绍 APPBP2 is a hydrophilic, microtubule binding protein that functions in the trafficking of Beta-Amyloid precursor protein. It is expressed in a variety of cell types and localizes to the cytoplasm. APPBP2 shares homology with kinesin light chain. It consists of a coiled-coil domain, PKC phosphorylation sites, four imperfect C-terminal tandem repeats, eight tetratricopeptide repeats and N- and C-terminal globular structures. APPBP2 recognizes and binds to the basolateral sorting sequence (BaSS) present in the cytoplasmic domain of the Beta-Amyloid precursor protein. In addition, APPBP2 interacts with the androgen receptor and suppresses androgen signaling.

Function : May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Subunit : Binds APP.

Subcellular Location : Nucleus. Cytoplasm

Post-translational modifications : Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.

Similarity : Contains 8 TPR repeats.

Database links : UniProtKB/Swiss-Prot: Q92624.2

我们应该如何储存抗体且最大限度地提高保质期，简单地说：

抗体应在（-20℃）中冷冻干燥或浓缩的液体形式，直到需要，避免反复冷冻/解冻周期，降低抗体含量和浓度。相反，冻结在单次使用的等分试样重组抗体或添加防冻剂（甘油或乙二醇），从而使料液可以保持在-20℃下为液体形式，以使移液没有“解冻”。

在4℃下存放，避免抗体（或其他蛋白质溶液）超过几天浓缩存量（> 0.5毫克）通常是稳定的，β淀粉样蛋白前体蛋白结合蛋白2抗体微生物添加剂，如叠氮化钠。不要试图保存稀释（<0.1mg/ml时）抗体溶液稳定，除非通过添加“载体”蛋白质或特殊添加剂。