Muellerian缪勒管激素抑制因子抗体

供货周期： 7天

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型号： 0.2ml/200μg

货号：

报价： ¥1

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产品介绍

Muellerian缪勒管激素抑制因子抗体勿使用无霜冷冻箱，因为会冷冻循环，这样会损伤抗体。

英文名称 Anti-AMH/MIS

中文名称 Muellerian缪勒管激素抑制因子抗体

别名 MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse

产品类型一抗

研究领域肿瘤细胞生物发育生物学信号转导干细胞生长因子和激素转录调节因子

蛋白分子量 predicted molecular weight: 57kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human AMH/MIS

Muellerian缪勒管激素抑制因子抗体亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Muellerian缪勒管激素抑制因子抗体产品介绍 Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Function : This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Subunit : Homodimer; disulfide-linked.

Subcellular Location : Secreted.

DISEASE : Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity : Belongs to the TGF-beta family.

Database links : UniProtKB/Swiss-Prot: P03971.3

我们应该如何储存抗体且最大限度地提高保质期，简单地说：

抗体应在（-20℃）中冷冻干燥或浓缩的液体形式，直到需要，避免反复冷冻/解冻周期，降低抗体含量和浓度。相反，冻结在单次使用的等分试样重组抗体或添加防冻剂（甘油或乙二醇），从而使料液可以保持在-20℃下为液体形式，以使移液没有“解冻”。

在4℃下存放，避免抗体（或其他蛋白质溶液）超过几天浓缩存量（> 0.5毫克）通常是稳定的，Muellerian缪勒管激素抑制因子抗体微生物添加剂，如叠氮化钠。不要试图保存稀释（<0.1mg/ml时）抗体溶液稳定，除非通过添加“载体”蛋白质或特殊添加剂。