重组人乙酰辅酶A乙酰转移酶2(Human ACAT2)

ACAT2 Human
Acetyl-Coenzyme A acetyltransferase 2 Human Recombinant
Catalog No. ENZ-295

Synonyms:
Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2.

Introduction:
Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Description:
Acetyl-Coenzyme A acetyltransferase 2 produced Human Recombinant in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-397 and having a total molecular mass of 41.3 kda. ACAT2 contains T7 tag at N-terminus.
ACAT-2 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
Acetyl-CoA acetyltransferase cytosolic in 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.

Stability:
ACAT2 although stable at 4°C for 1 week, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Applications:
• ELISA
• MS
• Inhibition Assays
• Western Blotting

Purity:
Greater than 95.0% as determined by SDS-PAGE.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.