Currently technology to utilize laser pulses for the treatment of hard tooth structure is in well underway. Research and development efforts by the Dental Sciences and equipment manufacturers have placed great emphasis on the need to develop accurate methods to characterize and guide the development of this new method of dental treatment. Infinitefocus microscopy is a method of imaging and quantifying microscopic three- dimensional features. This unique optical reconstruction technique is referred to as “Topomicroscopy”. It is ideally suited to the evaluation of laser (and conventional) dental drilling procedures because of its ability to produce geometricallyaccurate, 3D color images and the corresponding volumetric data sets of drilled dental surfaces.