天冬氨酸-胱氨酸特异性蛋白酶家族抗体
2015-02-02 08:33
浏览:44次
分享:
资料摘要:
天冬氨酸-胱氨酸特异性蛋白酶家族抗体
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq]. Also known as: caspase-1 isoform alpha p10 subunit; CASP 1; CASP1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BC; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme. CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p10.天冬氨酸-胱氨酸特异性蛋白酶家族抗体
下载本篇资料:
天冬氨酸胱氨酸特异性蛋白酶家族抗体.doc
22KB
推荐资料
大鼠胰岛素(INS)酶联免疫分析试剂盒用于测定大鼠血清,血浆及相关液体样本中胰岛素(INS)含量。本试剂盒仅供研究使用。
大鼠血管内皮生长因子 (VEGF)酶联免疫分析试剂盒用于测定大鼠血清,血浆及相关液体样本中血管内皮生长因子 (VEGF)含量。
大鼠胸肾表达趋化因子(BRAK/CXCL14)酶联免疫分析试剂盒用于测定大鼠血清、血浆及相关液体样本中胸肾表达趋化因子(BRAK/CXCL14)含量。
大鼠纤维蛋白原(FG)酶联免疫分析试剂盒用于测定大鼠血清血浆及相关液体样本中纤维蛋白原(FG)含量。