2019-06-05 15:08
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JASCO日本分光J-1500圆二色光谱仪
型号: J-1500
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品牌: 日本分光JASCO
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Biomedicine is a medicinal response to a physical or biological issue with the human body. Biomedicines use active ingredients derived from proteins and the research and development behind these methods is increasing daily. However, these biomedicines are more sensitive to environmental changes, such as a change in temperature, pH, and salt concentration, than traditional pharmaceuticals. To meet the demand for increased sample throughput in the modern pharmaceutical laboratory, JASCO has developed a fully automated high-throughput CD spectral measurement system. This system is composed of a J-1500 CD spectrometer with an autosampler unit. The high-throughput CD system enables the automation of sample pretreatment, injection and washing. In this application note, we will demonstrate the use of the ASU-800 automated system to evaluate the pH dependency on the structure of human serum albumin (HSA)
JASCO日本分光高通量圆二色光谱仪HT-CD的功能介绍,通过演示实验测试验证HT-CD系统的可靠性及重复性。
This application notes demonstrates the use of the J-1500 CD spectrometer and ATS-530 automatic titrator to monitor the interaction of HSA titrated with 3,5-diiodosalicylic acid. While 3,5-diiodosalicylic acid is achiral, its interaction with chiral HSA induces circular dichroism.
This application note demonstrates the high resolution CPL spectrum measurements of europium tris[3-(trifluorometh ylhydroxymethylene)-(+)-camphorate] (Eu(facam)3) using a CPL-300. Eu(facam) 3 is a common NMR shift reagent and has been used as a standard for CPL measurements. 2