Recombinant Cavia porcellus CTLA-4 (C-6His), Recombinant Cavia porcellus CTLA-4 (C-6His)

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产品描述：

产品名称：Recombinant Cavia porcellus CTLA-4 (C-6His)

背景说明: Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

描述: Recombinant Cavia porcellus Cytotoxic T-lymphocyte protein 4 is produced by our Yeast expression system and the target gene encoding Ala37-Asp161 is expressed with a 6His tag at the C-terminus.

氨基酸序列: AMHVAQPAVVLASSRGVASFECEYASSHNANEVRVTVLQQVASRTTEICAATYTVERELAFPEDS ACAGTSSGTRVNLTIQGLRAADTGLYICKVELMYPPPYFVGTGNGTQIYVIDPEPCPDSDHHHHH H

别名: Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4

Accession: H0VUB1

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Pichia pastoris

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

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