Namitecan

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抑制剂描述：

产品名称：Namitecan

产品别名：见爱必信官网

英文别名：Namitecan

靶点：Topoisomerase

CAS：372105-27-6

纯度：

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Namitecan is a potent topoisomerase I inhibitor, with antitumor property.

溶解性：DMSO*

体外研究：

Namitecan and cetuximab cooperate in inhibiting EGFR expression. Namitecan induces a dose-dependent decrease in EGFR expression in the different cell lines. ST1968 induces a comparable level of apoptosis in A431 and A431/TPT cells with IC50 of 0.21 and 0.29 μM.

体内研究：Namitecan and cetuximab cooperate in inhibiting EGFR expression. Namitecan induces a dose-dependent decrease in EGFR expression in the different cell lines. ST1968 induces a comparable level of apoptosis in A431 and A431/TPT cells with IC50 of 0.21 and 0.29 μM.

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