Protein degrader 1 hydrochloride

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抑制剂描述：

产品名称：Protein degrader 1 hydrochloride

产品别名：见爱必信官网

英文别名：Protein degrader 1 hydrochloride

靶点：E3 Ligand Plus Linker (VH032)

CAS：1448189-80-7

纯度：98%

外观：见爱必信官网

保存方法：store at -20℃ for one year（Powder）

描述：Protein degrader 1 hydrochloride is a small molecule ligand for VHL, an E3 ligase which has been targeted in numerous PROTACs.

溶解性：

体外研究：

Synthesis of HaloPROTACs contains Protein degrader 1 (Degradation Inducing Moiety A). Protein degrader 1 (Degradation Inducing Moiety A) is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. HaloPROTACs containing Protein degrader 1 (Degradation Inducing Moiety A) lead to nearly 70% degradation of GFP-HaloTag7, when sufficiently long linkers are used.

体内研究：Synthesis of HaloPROTACs contains Protein degrader 1 (Degradation Inducing Moiety A). Protein degrader 1 (Degradation Inducing Moiety A) is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. HaloPROTACs containing Protein degrader 1 (Degradation Inducing Moiety A) lead to nearly 70% degradation of GFP-HaloTag7, when sufficiently long linkers are used.

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