血小板白细胞C激酶底物同源结构域M2抗体

以下为您提供的是血小板白细胞C激酶底物同源结构域M2抗体的说明书,了解更多关于血小板白细胞C激酶底物同源结构域M2抗体的英文名称,血小板白细胞C激酶底物同源结构域M2抗体别名,血小板白细胞C激酶底物同源结构域M2抗体规格,请看以下详细介绍.

英文名称  Anti-PLEKHM2/SKIP 

中文名称 血小板白细胞C激酶底物同源结构域M2抗体

别    名  PH domain containing family M member 2; Pleckstrin homology domain containing family M (with RUN domain) member 2; Pleckstrin homology domain containing family M member 2; PLEKHM 2; RP11 169K16.1; Salmonella induced filaments A and kinesin interacting protein; SifA (Salmonella induced filaments A) and kinesin interacting protein; SifA and kinesin interacting protein; SKIP; KIAA0842; Novel RUN and PH domain containing protein. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Cow, Horse

血小板白细胞C激酶底物同源结构域M2抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

血小板白细胞C激酶底物同源结构域M2抗体的相关产品:

Rabbit Anti-human IgG F(ab')2/Cy5  Cy5标记的兔抗人IgG F(ab')2 0.1ml

Rabbit Anti-human IgG F(ab')2/Cy5.5  Cy5.5标记的兔抗人IgG F(ab')2 0.1ml

Rabbit Anti-human IgG F(ab')2/Cy7  Cy7标记的兔抗人IgG F(ab')2 0.1ml

产品类型  一抗    

研究领域  细胞生物 免疫学 细菌及  

蛋白分子量  predicted molecular weight: 122kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PLEKHM2 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Subunit : Interacts with KIF5B. Interacts with the S.typhimurium sifA protein; required for S.typhimurium infection.

Subcellular Location : Cytoplasm.

血小板白细胞C激酶底物同源结构域M2抗体Similarity : Contains 1 PH domain. 

Contains 1 RUN domain.