原钙粘附蛋白α4抗体

公司原钙粘附蛋白α4抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-PCDHA4 

中文名称  原钙粘附蛋白α4抗体 

别    名  CNR1; CNRN1; CRNR1; Ortholog of mouse CNR1; PCDA4_HUMAN; PCDH alpha 4; PCDH ALPHA4; PCDH-alpha-4; PCDHA 4; PCDHA4; Protocadherin alpha 4; Protocadherin alpha-4. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg
原钙粘附蛋白α4抗体的相关产品:

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原钙粘附蛋白α4抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Cow, Horse, Sheep 

产品类型  一抗    

研究领域  神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白  

蛋白分子量  predicted molecular weight: 99kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PCDHA4 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Members of the cadherin-related neuronal receptor (CNR) family, including PCDHA4 (also known as CNR1) and PCDHA6 (also known as CNR2), comprise a novel subfamily within the cadherin superfamily of adhesion molecules. The cadherin-related neuronal receptor proteins form a complex with Fyn, a protein tyrosine kinase that is involved in building brain networks and determining patterns of behavior. Cadherin-related neuronal receptor 1 and 2 were discovered during a search for receptor molecules to the Fyn signaling pathway in the mammalian brain. Members of the cadherin superfamily are Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The PCDHA4 and PCDHA6 extracellular domains contain six cadherin repeats that mediate Ca++-dependent cell adhesion, while the cytoplasmic domains are not homologous with other cadherins.

Function : Potential calcium-dependent cell-adhesion protein. May be involved 原钙粘附蛋白α4抗体in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location : Cell membrane.

Similarity : Contains 6 cadherin domains.

Database links : UniProtKB/Swiss-Prot: Q9UN74.1

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