以下为您提供的是原钙粘附蛋白α3抗体的说明书,了解更多关于原钙粘附蛋白α3抗体的英文名称,原钙粘附蛋白α3抗体别名,原钙粘附蛋白α3抗体规格,请看以下详细介绍.
英文名称 Anti-PCDHA3
中文名称 原钙粘附蛋白α3抗体
别 名 KIAA0345 like 11; PCDH alpha 3; Protocadherin alpha 3; PCDA3_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse
原钙粘附蛋白α3抗体的多样性:
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
因为抗体具有与抗原决定簇相对应的结合部位(抗原结合簇),所以抗体与抗原的结合具有特异性。另一方面,抗体本身是一种蛋白质,具有本身的氨基酸组成、排列和立体结构,对异种动物来说,它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性,它们表现出不同的血清学类型。
原钙粘附蛋白α3抗体的相关产品:
Rabbit Anti-Guinea pig IgM/Alexa Fluor 350 Alexa Fluor 350标记的兔抗豚鼠IgM 0.1ml
Rabbit Anti-Guinea pig IgM/Alexa Fluor 488 Alexa Fluor 488标记的兔抗豚鼠IgM 0.1ml
Rabbit Anti-Guinea pig IgM/Alexa Fluor 555 Alexa Fluor 555标记的兔抗豚鼠IgM 0.1ml
Rabbit Anti-Guinea pig IgM/Alexa Fluor 647 Alexa Fluor 647标记的兔抗豚鼠IgM 0.1ml
产品类型 一抗
研究领域 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白
蛋白分子量 predicted molecular weight: 99kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA3 (Protocadherin alpha-3) is a 950 amino acid single-pass transmembrane protein that contains six cadherin domains. PCDHA3 is a unique cadherin in that it likely functions in spermatogenesis and may also have a role in organizing germ cell-specific structures, such as the flagellum, acrosome and intercellular bridge. There are two isoforms of PCDHA13 that are produced as a result of alternative splicing events.
Function : PCDHA3 contains six cadherin domains. It is thought to be a calcium dependent cell adhesion protein and may be involved in the establishment and maintenance of specific neuronal connections in the brain. There are two named isoforms.
Su原钙粘附蛋白α3抗体bcellular Location : Cell membrane; Single pass type I membrane protein.
Similarity : Contains 6 cadherin domains.
Database links : UniProtKB/Swiss-Prot: Q9Y5H8.1
更多
企业名称
上海抚生实业有限公司
企业信息已认证
企业类型
信用代码
310112001171431
成立日期
2012-05-02
注册资本
50
经营范围
上海抚生实业有限公司
公司地址
上海闵行区七莘路
客服电话