磷酸化丝氨酸/苏氨酸抗体

公司磷酸化丝氨酸/苏氨酸抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-Phosphoserine/threonine 

中文名称 磷酸化丝氨酸/苏氨酸抗体 

别    名  phospho-Ser/Phospho-Thr; pS/pT; p-S/p-T; pSER/pThr; p-SER/p-Thr; p-Sp-T. 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg
磷酸化丝氨酸/苏氨酸抗体的相关产品:

Rabbit Anti-human IgM/Cy7  Cy7标记的兔抗人IgM 0.1ml

Rabbit Anti-human IgM/FITC  FITC标记的兔抗人IgM 0.3ml

Rabbit Anti-human IgM/Gold  胶体金标记的兔抗人IgM 0.5ml 

磷酸化丝氨酸/苏氨酸抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Phosphoserine/threonine  

产品类型  一抗  磷酸化抗体   

研究领域  肿瘤 细胞生物 神经生物学 信号转导 激酶和磷酸酶  

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthesised phosphopeptide contain Phosphoserine and Phosphothreonine 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC 磷酸化丝氨酸/苏氨酸抗体isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The Phospho-(Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.

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