公司6磷酸果糖激酶1抗体具有高纯度、高效价、高特异性的特点,仅用于科学研究,不可用于临床诊断及药物治疗,可以应用于多种实验。CST、Santa抗体品牌。
英文名称 Anti-PFK1
中文名称 6磷酸果糖激酶1抗体
别 名 6 phosphofructo 1 kinase/fructose 1,6 bisphosphatase; iPFK 1; IPFK1; PFK-1; PFK1; F16P1_HUMAN; Fructose-1,6-bisphosphatase 1;D-fructose-1,6-bisphosphate 1-phosphohydrolase 1..
浓 度 1mg/1ml
规 格 0.2ml/200μg
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6磷酸果糖激酶1抗体抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 心血管 细胞生物 信号转导 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 62kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PFK1 (1-100aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2), and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B), and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, Inducible PFK-2) and PFK-2 testis (PFKFB4).
S6磷酸果糖激酶1抗体ubunit : Homotetramer.
Tissue Specificity : Ubiquitous.
Similarity : In the C-terminal section; belongs to the phosphoglycerate mutase family.
Database links : UniProtKB/Swiss-Prot: P09467.5
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企业名称
上海抚生实业有限公司
企业信息已认证
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信用代码
310112001171431
成立日期
2012-05-02
注册资本
50
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上海抚生实业有限公司
公司地址
上海闵行区七莘路
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