公司神经元PAS结构域蛋白5抗体具有高纯度、高效价、高特异性的特点,仅用于科学研究,不可用于临床诊断及药物治疗,可以应用于多种实验。CST、Santa抗体品牌。
英文名称 Anti-PASD5/NPAS1
中文名称 神经元PAS结构域蛋白5抗体
别 名 Basic-helix-loop-helix-PAS protein MOP5; bHLHe11; Member of PAS protein 5; MOP5; Neuronal PAS domain protein 1; Neuronal PAS1; NPAS1; NPAS1_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
神经元PAS结构域蛋白5抗体的相关产品:
Rabbit anti-MG IgG/PE-CY5 PE-CY5标记的兔抗长爪沙鼠IgG 0.1ml
Rabbit anti-MG IgG/PE-Cy5.5 PE-Cy5.5标记的兔抗长爪沙鼠IgG 0.1ml
Rabbit anti-MG IgG/PE-Cy7 PE-Cy7标记的兔抗长爪沙鼠IgG 0.1ml
Rabbit anti-MG IgG/RBITC 罗丹明标记的兔抗长爪沙鼠IgG 0.3ml
神经元PAS结构域蛋白5抗体抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
产品类型 一抗
研究领域 神经生物学 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 63kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PASD5/NPAS1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Members of the bHLH-PAS family are transcription factors that contain a basic helix-loop-helix (bHLH) DNA-recognition motif which is located N-terminal to a PAS domain comprised of two imperfect direct repeats. Human NPAS1 is a deduced 590-amino acid protein which shares 86% sequence homology with mouse Npas1. In order for NPAS1 to bind DNA efficiently, it must form a dimer with another bHLH protein. NPAS1 interacts with ARNT (aryl hydrocarbon receptor nuclear translocator), and shows predominant expression in brain tissue. NPAS1 is also implicated in the control of regulatory pathways relevant to schizophrenia and to psychotic illness, and may play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen levels. The NPAS1 gene maps to human chromosome 19q13.2-q13.3.
Function : PASD5 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of PASD5 is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development.
Subunit : Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ARNT
Subcellular Location : Nuclear
Similarity : Contains 1 bHLH (basic helix-loop-helix) domain.
神经元PAS结构域蛋白5抗体Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains.
Database links : UniProtKB/Swiss-Prot: Q99742.2
公司提供神经元PAS结构域蛋白5抗体价格绝对优势,欢迎新老客户来电垂询我公司优质抗体神经元PAS结构域蛋白5抗体说明书及报价等。
更多
企业名称
上海抚生实业有限公司
企业信息已认证
企业类型
信用代码
310112001171431
成立日期
2012-05-02
注册资本
50
经营范围
上海抚生实业有限公司
公司地址
上海闵行区七莘路
客服电话