棕榈酰蛋白水解酶2抗体

以下为您提供的是棕榈酰蛋白水解酶2抗体的说明书,了解更多关于棕榈酰蛋白水解酶2抗体的英文名称,棕榈酰蛋白水解酶2抗体别名,棕榈酰蛋白水解酶2抗体规格,请看以下详细介绍.

英文名称  Anti-PPT2 

中文名称  棕榈酰蛋白水解酶2抗体 

别    名  Lysosomal thioesterase PPT2; Palmitoyl protein hydrolase 2; Palmitoyl protein thioesterase 2; PPT 2; PPT-2; Ppt2; PPT2_HUMAN; S thioesterase G14; S-thioesterase G14. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse

棕榈酰蛋白水解酶2抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

棕榈酰蛋白水解酶2抗体的相关产品:

Rabbit Anti-Monkey IgG/PE  PE标记的兔抗猴IgG 0.1ml

Rabbit Anti-Monkey IgG/PE-Cy3  PE-Cy3标记的兔抗猴IgG 0.1ml

Rabbit Anti-Monkey IgG/PE-CY5  PE-CY5标记的兔抗猴IgG 0.1ml

Rabbit Anti-Monkey IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗猴IgG 0.1ml

产品类型  一抗    

研究领域  细胞生物 神经生物学  

蛋白分子量  predicted molecular weight: 31kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PPT2 (221-302aa) 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 PPT2 (palmitoyl-protein thioesterase 2), also known as G14, is a 302 amino acid glycosylated protein that localizes to the lysosome and belongs to the palmitoyl-protein thioesterase family. Expressed throughout the body with highest levels in skeletal muscle, PPT2 functions to remove thioester-linked fatty acyl groups from a variety of substrates, including S-palmitoyl-CoA, thereby playing an important role in lipid metabolism. PPT2 operates at an optimal pH of 7 and exhibits the highest activity for the acyl groups on myristic and palmitic acids, with lower levels of activity toward other short- and long-chain acyl substrates. PPT2 exists as two isoforms, one of which is expressed at low levels and is catalytically inactive.

Function : Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.

Subcellular Location : Lysosome.

棕榈酰蛋白水解酶2抗体Tissue Specificity : Broadly expressed, with highest levels in skeletal muscle.

Similarity : Belongs to the palmitoyl-protein thioesterase family.

Database links : UniProtKB/Swiss-Prot: Q9UMR5.4