细胞色素氧化酶装配因子PET112抗体

以下为您提供的是细胞色素氧化酶装配因子PET112抗体的说明书,了解更多关于细胞色素氧化酶装配因子PET112抗体的英文名称,细胞色素氧化酶装配因子PET112抗体别名,细胞色素氧化酶装配因子PET112抗体规格,请看以下详细介绍.

英文名称  Anti-PET112L 

中文名称  细胞色素氧化酶装配因子PET112抗体 

别    名  Cytochrome oxidase assembly factor PET112 homolog; GATB_HUMAN; GLU-ADT subunit B; HSPC199; mitochondrial; PET112; PET112 homolog (yeast); PET112-like; Probable glutamyl-tRNA(Gln) amidotransferase subunit B. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Cow

细胞色素氧化酶装配因子PET112抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

细胞色素氧化酶装配因子PET112抗体的相关产品:

Rabbit Anti-MK IgM/Cy5.5  Cy5.5标记的兔抗猴IgM 0.1ml

Rabbit Anti-MK IgM/Cy7  Cy7标记的兔抗猴IgM 0.1ml

Rabbit Anti-MK IgM/PE  PE标记的兔抗猴IgM 0.1ml

产品类型  一抗    

研究领域  细胞生物 信号转导 表观遗传学  

蛋白分子量  predicted molecular weight: 58kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PET112L 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.

Function : Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

Subunit : Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (PET112) and C (GATC) subunits. 

Subcellular Location : Mitochondrion.

Tissue Specificity : Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle and heart.

细胞色素氧化酶装配因子PET112抗体Similarity : Belongs to the gatB/gatE family. GatB subfamily.

Database links : UniProtKB/Swiss-Prot: O75879.1