肠道71型/手足口病抗体

公司肠道71型/手足口病抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-EV71 polyprotein VP1 

中文名称  肠道71型/手足口病抗体 

别    名  EV71; Enterovirus 71; VP1 [Human enterovirus 71];polyprotein VP1; Human enterovirus 71. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg
肠道71型/手足口病抗体的相关产品:

Rabbit Anti-rat IgG/PE-Cy7  PE-Cy7标记的兔抗大鼠IgG 0.1ml

Rabbit Anti-rat IgG/RBITC  罗丹明标记的兔抗大鼠IgG 0.3ml

Rabbit Anti-rat IgM  兔抗大鼠IgM 1mg

Rabbit anti-Rat IgM whole serum  兔抗大鼠IgM抗血清 1ml

肠道71型/手足口病抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  enterovirus71  

产品类型  一抗    

研究领域  细胞生物 细菌及  

蛋白分子量  predicted molecular weight: 33/351kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from EV71 polyprotein VP1 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Enteroviruses, such as enterovirus 71, are classified to be in the picornavirus family, pico [small] + RNA [ribonucleic acid] + virus. Picornaviruses are among the smallest and simplest ribonucleic acid containing viruses known (1). The RNA for many enteroviruses have now been cloned and complete genomic sequences have been obtained. The RNA from all sequenced enteroviruses are similar in length, about 7400 nucleotides, and have identical organization (1). The human alimentary tract is the predominant site of enterovirus replication and these viruses were first isolated from enteric specimens. These viruses are the cause of paralytic poliomyelitis, aseptic meningitis-encephalitis, myocarditis, pleurodynia, hand-foot-and-mouth disease, conjunctivitis, and numerous other syndromes associated with extra-intestinal target organs. There are 67 numbered types of enteroviruses in the enterovirus family (1): three polioviruses, twenty-three coxsackieviruses A, six coxsackieviruses B, thirty-one echoviruses, and four other enteroviruses. 

肠道71型(Human enterovirus 71)简称EV71。肠在学上的分类是属于微小科(picornaviridae)中的肠群(enterovirus)。

EV 71为目前肠群中最新发现的，其感染性强且致病率高，尤其是神经系统方面的并发症。EV71主要引起手足口病，还可引起无菌性脑膜炎、脑干脑炎和脊髓灰质炎样的麻痹等多种神经系统疾病。手足口病和中枢神经系统感染是EV71感染而引起的两大常见临床症状。

肠道71型/手足口病抗体肠道71型从咽部或肠道侵入，在局部黏膜或淋巴组织中繁殖，并由局部排出，此时可引起局部症状。继而又侵入局部淋巴结，并由此进入血液循环导致第一次血症。经血循环侵入网状内皮组织、深层淋巴结、肝、脾、骨髓等处大量繁殖并由此进入血液循环，引起第二次血症。可随血流进入全身各器官，如中枢神经系统、皮肤黏膜、心脏等处，进一步繁殖并引起病变。

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