蛋白酪氨酸磷酸酶相互作用蛋白51抗体

公司蛋白酪氨酸磷酸酶相互作用蛋白51抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-PTPIP51/FAM82A2 

中文名称 蛋白酪氨酸磷酸酶相互作用蛋白51抗体 

别    名  Cerebral protein 10; Family with sequence similarity 82 member C; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51; Regulator of microtubule dynamics 3; Regulator of microtubule dynamics protein 3; RMD 3; RMD3; TCPTP interacting protein 51; RMD3_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg
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蛋白酪氨酸磷酸酶相互作用蛋白51抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Horse, Rabbit  

产品类型  一抗    

研究领域  肿瘤 细胞生物 免疫学 细胞周期蛋白  

蛋白分子量  predicted molecular weight: 52kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PTPIP51/FAM82A2 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 FAM82A2, or family with sequence similarity 82, member C, may participate in differentiation and apoptosis of keratinocytes. Overexpression of FAM82A2 induces apoptosis.

Function : Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.

Subunit : Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB.

Subcellular Location : Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.

Tissue Specificity : Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the h蛋白酪氨酸磷酸酶相互作用蛋白51抗体ippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed.

Similarity : Belongs to the RMDN family.

Database links : UniProtKB/Swiss-Prot: Q96TC7.2

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