以下为您提供的是早幼粒细胞白血病锌指蛋白抗体的说明书,了解更多关于早幼粒细胞白血病锌指蛋白抗体的英文名称,早幼粒细胞白血病锌指蛋白抗体别名,早幼粒细胞白血病锌指蛋白抗体规格,请看以下详细介绍.
英文名称 Anti-Plzf
中文名称 早幼粒细胞白血病锌指蛋白抗体
别 名 Promyelocytic leukemia zinc finger protein; ZBT16_HUMAN; ZBTB16; Zfp145; Zinc finger and BTB domain containing 16; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145 (Kruppel like expressed in promyelocytic leukemia); Zinc finger protein 145; Zinc finger protein PLZF; Znf145.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse
早幼粒细胞白血病锌指蛋白抗体的多样性:
抗体的异质性。抗体的组成极为复杂,是由成千上万、多种多样的免疫球蛋白(Ig)分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上,既相似,又有差别。由于有差别,它们的电泳活性就有很大的变化。
因为抗体具有与抗原决定簇相对应的结合部位(抗原结合簇),所以抗体与抗原的结合具有特异性。另一方面,抗体本身是一种蛋白质,具有本身的氨基酸组成、排列和立体结构,对异种动物来说,它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性,它们表现出不同的血清学类型。
早幼粒细胞白血病锌指蛋白抗体的相关产品:
RISC/Serine carboxypeptidase 1 丝氨酸羧肽酶1抗体 0.2ml
RIT1 RIT1蛋白抗体 0.2ml
RKIP/PBP 磷脂酰乙醇胺结合蛋白1抗体 0.1ml
RLBP1L1 视黄醛结合蛋白1抗体 0.2ml
产品类型 一抗
研究领域 肿瘤 细胞生物 发育生物学 干细胞
蛋白分子量 predicted molecular weight: 74kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Plzf (601-673aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Function : Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subunit : Binds EPN1. Interacts with ZBTB32 and CUL3.
Subcellular Location : Nucleus.
Tissue Specificity : Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
DISEASE : Defects in ZBTB16 are the cause of skeletal defects genital hypoplasia and mental retardation (SGYMR) [MIM:612447]. A disorder characterized by mental retardation, craniofacial dysmorphism, microcephaly and short stature. Additional features include absence of the thumbs, hypoplasia of the radii and ulnae, additional vertebrae and ribs, retarded bone age and genital hypoplasia.
Note=A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.
早幼粒细胞白血病锌指蛋白抗体Similarity : Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 9 C2H2-type zinc fingers.
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企业名称
上海抚生实业有限公司
企业信息已认证
企业类型
信用代码
310112001171431
成立日期
2012-05-02
注册资本
50
经营范围
上海抚生实业有限公司
公司地址
上海闵行区七莘路
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