免疫球蛋白超家族成员3抗体

以下为您提供的是免疫球蛋白超家族成员3抗体的说明书,了解更多关于免疫球蛋白超家族成员3抗体的英文名称,免疫球蛋白超家族成员3抗体别名,免疫球蛋白超家族成员3抗体规格,请看以下详细介绍.

英文名称  Anti-IGSF3

中文名称  免疫球蛋白超家族成员3抗体

别    名  EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN.

浓    度  1mg/1ml

规 格  0.2ml/200μg    

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

免疫球蛋白超家族成员3抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

免疫球蛋白超家族成员3抗体的相关产品:

Anti-SRG2   突触结合蛋白相关基因2抗体 0.2ml

Anti-SSA/RO   核糖核蛋白抗原SSA抗体 0.1ml

Anti-SSB/La   抗干燥症SSB/La抗体 0.2ml

Anti-SSTR1   生长抑素受体1抗体 0.2ml

产品类型  一抗    

研究领域  细胞生物 细胞粘附分子 细胞表面分子  

蛋白分子量  predicted molecular weight: 133kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IGSF3

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule.

Subcellular Location : Membrane; Single-pass type I membrane protein

Tissue Specificity : It is expressed in a wide range of tissues with high expression in placenta, kidney and lung.

免疫球蛋白超家族成员3抗体Similarity : Contains 8 Ig-like C2-type (immunoglobulin-like) domains.

Database links : UniProtKB/Swiss-Prot: O75054.3