免疫球蛋白超家族成员12抗体

以下为您提供的是免疫球蛋白超家族成员12抗体的说明书,了解更多关于免疫球蛋白超家族成员12抗体的英文名称,免疫球蛋白超家族成员12抗体别名,免疫球蛋白超家族成员12抗体规格,请看以下详细介绍.

英文名称  Anti-IGSF12/CD300

中文名称  免疫球蛋白超家族成员12抗体

别    名  CD300 antigen-like family member A; CD300a; CD300a molecule; CLM-8; CLM8_HUMAN; CMRF 35 H9; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H leukocyte immunoglobulin like receptor; CMRF35H9; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; Leukocyte membrane antigen; Mast cell derived paired immunoglobulin like receptor 1; NK inhibitory receptor; Polymeric immunoglobulin receptor 4.

浓    度  1mg/1ml

规 格  0.2ml/200μg    

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human

免疫球蛋白超家族成员12抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

免疫球蛋白超家族成员12抗体的相关产品:

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Anti-Tenascin   固生蛋白抗体 1ml

Anti-Tenascin/TN   细胞粘合素抗体 0.1ml

Anti-TFF3   三叶肽因子3抗体 0.1ml

产品类型  一抗    

研究领域  免疫学 细胞类型标志物  

蛋白分子量  predicted molecular weight: 31kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IGSF12/CD300

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

Function : Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

Subunit : Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.

Subcellular Location : Cell membrane; Single-pass type I membrane protein (Potential).

Tissue Specificity : Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.

Post-translational modifications : Phosphorylated on tyrosine.

免疫球蛋白超家族成员12抗体Similarity : Belongs to the CD300 family.

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links : UniProtKB/Swiss-Prot: Q9UGN4.2