白介素6抗体

公司白介素6抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-IL-6

中文名称  白介素6抗体

别    名  Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmacytoma growth factor; IFNB2; IL 6; IL6 protein; Interferon beta 2; Interleukin 6 (interferon beta 2); Interleukin 6; Interleukin6; IL6_HUMAN.

浓    度  1mg/1ml

规 格  0.1ml/100μg  0.2ml/200μg  
白介素6抗体的相关产品:

Anti-Visfatin-1/PBEF1 hu、 mo、 rat、MK   内脂素/内脏脂肪素 0.1ml

Anti-VSIG4 Antibody   T淋巴细胞负调节蛋白之一抗体 0.2ml

Anti-VTG   卵黄蛋白原抗体 0.2ml

Anti-VWF   血管假性血友病因子/血管性血友病因子抗体 0.1ml  

白介素6抗体抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Dog, Pig, Cow, Horse, Sheep

产品类型  一抗    

研究领域  肿瘤 细胞生物 生长因子和激素 转录调节因子  

蛋白分子量  predicted molecular weight: 23kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IL-6 (51-150aa)

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].

Function : Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Subcellular Location : Secreted.

Post-translational modifications : N- and O-glycosylated.

DISEASE : Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.

Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.

Similarity : Belongs to the IL-6 superfamily.

Database links :

UniProtKB/Swiss-Prot: P05231.1 (human)

UniProtKB/Swiss-Prot: P08505.1 (mouse)

Entrez Gene: 3569 Human

SwissProt: P05231 Human

U白介素6抗体nigene: 654458 Human

白细胞介素6是一种多功能细胞因子，既可由淋巴细胞产生，也能由非淋巴细胞合成。在体内免疫反应调节、血细胞的增生、防御机制和急性期反应中起重要作用。 白细胞介素-6是一种糖蛋白，它既可诱导急性期时相关蛋白的产生，也是β细胞终末分化并分泌抗体的必需因子，在免疫调节中发挥重要作用，人的IL-6的前体有212个氨基酸。成熟形态为185个氨基酸。白细胞介素6的分子量：21KD-28KD

公司提供白介素6抗体价格绝对优势，欢迎新老客户来电垂询我公司优质抗体：白介素6抗体说明书及报价等。