细胞表面免疫球蛋白样转录因子2抗体

公司细胞表面免疫球蛋白样转录因子2抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-ILT2/CD85j

中文名称  细胞表面免疫球蛋白样转录因子2抗体

别    名  LILRB1; Leukocyte immunoglobulin-like receptor subfamily B member 1; Leukocyte immunoglobulin-like receptor 1; LIR-1; Immunoglobulin-like transcript 2; Monocyte/macrophage immunoglobulin-like receptor 7; ILT-2; MIR-7; CD85 antigen-like family member J; CD85j; ILT2; LIR1; MIR7; CD85; CD85 antigen; CD85j antigen; Ig like transcript 2; leukocyte Ig like receptor 1.

浓    度  1mg/1ml

规 格  0.2ml/200μg  
细胞表面免疫球蛋白样转录因子2抗体 的相关产品:

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Anti-TmR2   胶质细胞系源性神经营养因子受体β抗体 0.2ml

anti-Tn-C   腱糖蛋白-C抗体 0.2ml  

细胞表面免疫球蛋白样转录因子2抗体抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human

产品类型  一抗    

研究领域  免疫学 细胞膜受体  

蛋白分子量  predicted molecular weight: 72kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human ILT2 (151-190aa)

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

细胞表面免疫球蛋白样转录因子2抗体Subunit : Binds PTPN6 when phosphorylated. Binds FCGR1A.

Subcellular Location : Membrane; Single-pass type I membrane protein.

Tissue Specificity : Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.

Similarity : Contains 4 Ig-like C2-type (immunoglobulin-like) domains.

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