免疫球蛋白lambda样肽1抗体

公司免疫球蛋白lambda样肽1抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-IGLL1

中文名称  免疫球蛋白lambda样肽1抗体

别    名  14.1; AGM2; CD179 antigen-like family member B; CD179B; CD179b antigen; Ig lambda 5; Ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; Igll1; IGLL1_HUMAN; IGO; IGVPB; Immunoglobulin lambda like polypeptide 1 precursor; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; Immunoglobulin omega polypeptide chain; Immunoglobulin related protein 14.1; Immunoglobulin-related protein 14.1; Lambda5; Pre B lymphocyte specific protein 2; VPREB2.

浓    度  1mg/1ml

规 格  0.2ml/200μg  
免疫球蛋白lambda样肽1抗体的相关产品:

Anti-TTF-1   甲状腺核转录因子-1/甲状腺特异增强子结合蛋白抗体 0.1ml

Anti-TTF-2   甲状腺转录因子-2抗体 0.1ml

Anti-Tubulin-α   微管蛋白抗体 0.1ml

Anti-Tubulin-γ   微管蛋白-γ抗体 0.1ml  

免疫球蛋白lambda样肽1抗体抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human

产品类型  一抗    

研究领域  细胞生物 免疫学 b-淋巴细胞  

蛋白分子量  predicted molecular weight: 19kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IGLL1

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function : Critical for B-cell development.

Subunit : Associates non-covalently with VPREB1.

Subcellular Location : Secreted.

Tissue Specificity : Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).

免疫球蛋白lambda样肽1抗体DISEASE : Agammaglobulinemia 2 (AGM2) [MIM:613500]: A primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity : Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Database links : UniProtKB/Swiss-Prot: P15814.1

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