RecQ解旋酶样蛋白5抗体

英文名称    RECQL5    

中文名称    RecQ解旋酶样蛋白5抗体    

别    名    ATP-dependent DNA helicase Q5; DNA helicase, RecQ like type 5; DNA helicase, RECQ-like, type 5; RecQ helicase protein-like 5 beta; RecQ protein-like 5; RecQ protein-like 5, isoform CRA_b; RecQ5; Recq5b; Recql5b.    

RecQ解旋酶样蛋白5抗体      

说 明 书    0.2ml      

研究领域    染色质和核信号  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    109kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RECQL5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RecQ解旋酶样蛋白5抗体产品介绍    background:
RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.

Function:
May have an important role in DNA metabolism. 

Subunit:
Interacts with TOP3A and TOP3B. 

Subcellular Location:
Cytoplasmic and Nuclear, depending on the isoform.

Tissue Specificity:
Ubiquitous

Similarity:
Belongs to the helicase family. RecQ subfamily. 
Contains 1 helicase ATP-binding domain. 
Contains 1 helicase C-terminal domain. 

Database links:
UniProtKB/Swiss-Prot: O94762.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RecQ解旋酶样蛋白5抗体

A-53-1 COX IgG VI  柯萨奇病毒 IgG Ⅵ(间接法二步法)

A-54-1 RSV IgG  合胞病毒 IgG(间接法二步法)

A-09-1 RSV IgM  合胞病毒 IgM(间接法二步法)

A-55-1 ECV IgG  艾柯病毒 IgG(间接法二步法)

A-10-1 ECV IgM  艾柯病毒 IgM(间接法二步法)

A-56-1 Rotavirus IgG  轮状病毒 IgG(间接法二步法)

A-11-1 Rotavirus IgM  轮状病毒 IgM(间接法二步法)

A-57-1 ADV IgG III  腺病毒 IgG Ⅲ型(间接法二步法)

A-12-1 ADV IgM III  腺病毒 IgM Ⅲ型(间接法二步法)

A-58-1 ADV IgG VII  腺病毒 IgG Ⅶ型(间接法二步法)

A-13-1 ADV IgM VII  腺病毒 IgM Ⅶ型(间接法二步法)

A-14-1 ADV IgM XI  腺病毒 IgM Ⅺ型(间接法二步法)

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hz-1013 Mouse carcinohzbryonic antign,CEA ELISA Kit   小鼠癌胚抗原

hz-1013 IFN- Omega (Human Interferon Omega ,IFN- Omega ) ELISA Kit  人ω干扰素

EF-1013 IL-1 Alpha ELISA kit  鱼类白介素1α

hz-1013 MT/MLT (Rat Melatonin,MT/MLT) ELISA Kit  大鼠褪黑素

A-59-1 ADV IgG XI  腺病毒 IgG Ⅺ型(间接法二步法)

A-60-1 ADV IgG  腺病毒 IgG 混合型(间接法二步法)

A-20-1 ADV IgM  腺病毒 IgM 混合型(间接法二步法)

A-61-1 EB-VCA IgG  EB 病毒 IgG(间接法二步法)

A-17-1 EB-VCA IgM  EB 病毒 IgM(间接法二步法)

A-62-1 MP IgG  肺炎支原体 IgG(间接法二步法)

A-22-1 MP IgM  肺炎支原体 IgM(间接法二步法)

A-63-1 IFV IgG/IFV-A IgG   流感病毒A IgG(间接法二步法) ELISA试剂盒

A-24-1 IFV IgM/IFV-A IgM  流感病毒A IgM(间接法二步法)ELISA试剂盒

A-64-1 PIV IgG  付流感病毒 IgG(间接法二步法)

A-25-1 PIV IgM  付流感病毒 IgM(间接法二步法)

A-65-1 hzF IgG  流行性出血热病毒 IgG(间接法二步法)

A-31-1 hzF IgM  流行性出血热病毒 IgM(间接法二步法)

A-66-1 MU IgG  流行性腮腺炎病毒 IgG(间接法二步法)

A-67-1 MU IgM  流行性腮腺炎病毒 IgM(间接法二步法)

A-68-1 EPBV IgG  乙型脑炎病毒 IgG(间接法二步法)

A-69-1 EPBV IgM  乙型脑炎病毒 IgM(间接法二步法)

E-79-48/96 Beta-HCG  人绒毛膜促性腺激素(夹心法一/二步法)

EF-1014 IL-1 Beta ELISA Kit  鱼类白介素1β

EA-1014 Plg (Rabbit Plasminogen) ELISA Kit  兔子纤溶酶原

hz-1014 Mouse Cluster of differentiation 19,CD19 ELISA Kit  小鼠CD19分子