视网膜感光细胞外节膜蛋白1抗体

英文名称    ROM1    

中文名称    视网膜感光细胞外节膜蛋白1抗体    

别    名    Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23.    

视网膜感光细胞外节膜蛋白1抗体   

说 明 书    0.1ml  0.2ml      

研究领域    神经生物学  细胞粘附分子  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ROM1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

视网膜感光细胞外节膜蛋白1抗体产品介绍    background:
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008]. 

Function:
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.

Subcellular Location:
Membrane; Multi-pass membrane protein. 

Tissue Specificity:
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

DISEASE:
Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2.

Similarity:
Belongs to the PRPH2/ROM1 family.

Database links:
UniProtKB/Swiss-Prot: Q03395.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

视网膜感光细胞外节膜蛋白1抗体

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