RAS相关GTP结合蛋白C抗体

英文名称    RRAGC    

中文名称    RAS相关GTP结合蛋白C抗体    

别    名    RAGC; TIB929; YGR163W; GTPase interacting protein 2; GTPase-interacting protein 2; GTR2; Rag C; Rag C protein; Ras related GTP binding C; Ras-related GTP-binding protein C; RP23 29H22.4; RRAGC; RRAGC_HUMAN.    

RAS相关GTP结合蛋白C抗体        

说 明 书    0.2ml      

研究领域    细胞生物  染色质和核信号  信号转导  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    44kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RRAGC    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. RAS相关GTP结合蛋白C抗体产品介绍    background:
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].

Function:
Has guanine nucleotide-binding activity but weak intrinsic GTPase activity. Probably required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.

Subunit:
Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.

Subcellular Location:
Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.

Similarity:
Belongs to the GTR/RAG GTP-binding protein family.

Gene ID:
64121

Database links:

Entrez Gene: 64121 Human

Entrez Gene: 54170 Mouse

Entrez Gene: 100528436 Pig

Entrez Gene: 298514 Rat

Omim: 608267 Human

SwissProt: Q9HB90 Human

SwissProt: Q99K70 Mouse

Unigene: 532461 Human

Unigene: 220922 Mouse

Unigene: 473825 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RAS相关GTP结合蛋白C抗体

hz-2203P Integrin alpha V  巨噬细胞来源的趋化因子αV多肽

hz-5551P phospho-AMPK alpha-1/PRKAA1(Thr198) peptide  磷酸化腺苷单磷酸活化蛋白激酶α1抗原

hz-0035P CREB-1 (cAMP responsive elhzent binding protein-1)  环腺苷酸应答元件结合蛋白（抗原）

hz-0036P phospho-CREB-1   磷酸化环腺苷酸应答元件结合蛋白（多肽）

hz-1062P ADRA2 peptide  肾上腺素能受体2抗原

hz-0246P CRF (Corticotropin-Releasing Factor)  促肾上腺皮质激素释放因子

hz-0063P CT (Calcitonin )  降钙素（抗原）

hz-0124P CT-R (Calcitonin receptor)  降钙素受体（抗原）

hz-5907P Ferritin peptide  铁蛋白抗原

hz-0013P Cytochrome C  细胞色素 C（抗原）

hz-1063P ADRB3/ Beta3-AR ( Beta3-adrenergic receptor)  肾上腺素能受体β3

hz-0271P Cytomegalovirus (CMV)PP65  细胞巨化病毒(多肽)

hz-0180P DDC (DOPA decarboxylase)  多巴胺脱羧酶（抗原）

hz-0405P EGFR- V III  人表皮生长因子受体-8（多肽片断抗原）

hz-2045P Alpha-AF/ Alpha-Afa(alpha-L-arabinofuranosidase)  α-L-阿拉伯呋喃糖苷酶抗原

hz-6282P SCCA peptide  鳞状细胞癌抗原

hz-0202P Endothelin-1  内皮素-1(多肽抗原)

hz-0188P Endothelin-1 (ET-1)  内皮素-1（抗原）

hz-0021P ERAB   内质网Aβ相关结合蛋白（抗原）

hz-0122P ER-Alpha peptide  雌激素受体（多肽抗原）

hz-0415P TIMP-1(Tissue Inhibitor of Metalloproteinase-1)  金属蛋白酶组织抑制因子-1（抗原）

hz-0174P ER-Alpha/ Beta Estrpgen Receptor Alpha/ Beta  雌激素受体（抗原）

hz-0116P ER- Beta (Estrogen receptor beta)peptide  雌激素受体（多肽抗原）

hz-1223P Aggrecan  软骨蛋白聚糖/可聚蛋白多糖抗原

hz-0243P EXPB-2  植物延展素-β（抗原）

hz-0332P factor VIII  第八因子相关抗原(多肽片断抗原)

hz-0215P FAS (Apo-a1; CD95;)(抗原)  载脂蛋白-a1

hz-1176P Agrin peptide  聚集蛋白抗原

hz-2132P Agtr1/AT1a(Angiotensin II receptor, type 1a)  血管组织血管紧张素Ⅱ1型受体抗原

hz-0216P FasL(抗原)  

hz-1416P Ah Receptor(Aryl Hydrocarbon Receptor)  芳香烃受体抗原

hz-0110P Fe65 protein peptide  Fe65 蛋白（多肽抗原）