钠离子通道调节蛋白1抗体

英文名称    SCNM1    

中文名称    钠离子通道调节蛋白1抗体    

别    名    SCNM 1; Sodium channel modifier 1.    

钠离子通道调节蛋白1抗体       

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  锌指蛋白  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    26kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SCNM1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

钠离子通道调节蛋白1抗体产品介绍    background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. SCNM1 (sodium channel modifier 1) is a 230 amino acid protein that contains one matrin-type zinc finger. Localized to the nucleus, SCNM1 is thought to function as an RNA splicing factor that may modify the expression of sodium channel-related proteins. SCNM1 exists as two alternatively spliced isoforms that are encoded by a gene which maps to chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1

Function:
SCNM1 (Sodium channel modifier 1) contains a matrin-type zinc finger. It is thought to function as an RNA splicing factor. It is a disease modifier gene, that modifies phenotypic expression of SCN8A mutations in mice and is required for efficient in vivo splicing of a mutant splice donor site in the sodium channel SCN8A.

Subcellular Location:
Nuclear

Database links:

Entrez Gene: 79005 Human

Omim: 608095 Human

SwissProt: Q9BWG6 Human

Unigene: 732060 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

钠离子通道调节蛋白1抗体

hz-7741R CDC3/CDC10/Septin 7  细胞周期调控因子3抗体

hz-7742R CEP55  中心体蛋白55kDa抗体

hz-7743R CEP97  中心体蛋白97kDa抗体

hz-7744R CHMP4B/CHMP4C  染色质修饰蛋白4B(4C)抗体

hz-7745R CKAP2  细胞骨架相关蛋白2/肿瘤和微管相关蛋白抗体

hz-7746R DCTN3  动力蛋白激活蛋白亚基3抗体

hz-7747R DCTN6  动力蛋白激活蛋白6抗体

hz-7748R FMN2  形成素2抗体（成蛋白）

hz-7749R HIST1H2AH  组蛋白H2A/S抗体

hz-7750R KIF20A/MKLP2  有丝分裂驱动蛋白样2抗体

hz-4170R TRIM25  雌激素反应锌指蛋白抗体

hz-5614R phospho-TRIM25(The91)  磷酸化雌激素反应指状蛋白抗体

hz-2914R TIP47/M6PRBP1  脂滴相关蛋白TIP47抗体

hz-2980R TLS/FUS  粘液样脂肪肉瘤蛋白FUS1抗体

hz-7751R KIF2B  有丝分裂驱动蛋白样2B抗体

hz-7752R KLHL13  kelch样蛋白13抗体

hz-5615R phospho-TRIM25(Ser100)  磷酸化雌激素反应指状蛋白抗体

hz-7753R KLHL9  kelch样蛋白9抗体

hz-7754R MKKS/BBS6  巴德-毕德氏综合征蛋白BBS6抗体

hz-7755R MSF/Cell division control protein septin D1  细胞周期调控蛋白D1抗体

hz-7756R MyoGEF  肌球蛋白相互作用G蛋白交换因子抗体

hz-7757R NAT10  乙酰基转移酶10抗体

hz-7758R NEK7  丝氨酸/苏氨酸蛋白激酶Nek7抗体

hz-7759R GGCX  γ-谷氨酰羧化酶抗体

hz-7760R Factor VII light chain  凝血因子VII

hz-7761R Myosin VIIa/DFNB2  肌球蛋白7a/常染色体隐性耳聋蛋白2抗体

hz-7762R Factor X  凝血因子10抗体

hz-7763R NIR2  膜磷脂转移蛋白1抗体

hz-7764R NUSAP1  核仁和纺锤体相关蛋白1抗体

hz-7765R RAB35  RAS相关蛋白癌基因Rab35抗体

hz-7766R RACGAP1  Rho GTP酶激活蛋白GAP抗体

hz-7767R phospho-RACGAP1(Ser387)  磷酸化Rho GTP酶激活蛋白GAP抗体

hz-7768R RCC2  染色体浓缩调节蛋白2抗体

hz-7769R SEPT1  细胞分化蛋白SEP1抗体