转钴胺素蛋白2抗体

英文名称    TCN2    

中文名称    转钴胺素蛋白2抗体    

别    名    Macrocytic anemia; TC; TC II; TC-2; TC2; TCII; TCN 2; TCO2_HUMAN; Transcobalamin 2; Transcobalamin II; Transcobalamin II; macrocytic anemia; Transcobalamin-2; Vitamin B12 binding protein 2.    

转钴胺素蛋白2抗体         

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  心血管  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    46kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TCN2/Transcobalamin II    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

转钴胺素蛋白2抗体  产品介绍    background:
Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.

Function:
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. 

Subcellular Location:
Secreted.

DISEASE:
Defects in TCN2 are the cause of transcobalamin II deficiency (TCN2 deficiency) [MIM:275350]. This results in various forms of anemia. 

Similarity:
Belongs to the eukaryotic cobalamin transport proteins family. 

Database links:

Entrez Gene: 6948 Human

Omim: 275350 Human

SwissProt: 275350 Human

SwissProt: P20062 Human

Unigene: 417948 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

Involvement in disease;Defects in TCN2 are the cause of transcobalamin II deficiency (TCN2 deficiency) [MIM:275350]. This results in various forms of anemia.    

转钴胺素蛋白2抗体  

hz-1606R CYP1A1  细胞色素P450 1A1抗体

hz-2589R P450 1A2/CYP1A2  细胞色素P450 1A2抗体

hz-3608R CYP11A1/P450SCC  细胞色素P450 11A1抗体

hz-2887R CYP2C9  细胞色素P450 2C9抗体

hz-3898R CYP11B1  细胞色素P450 11B1抗体

hz-4108R Cytochrome P450 2D1  细胞色素CYP2D1抗体

hz-1742R CYP3A4  细胞色素P450 3A4抗体

hz-2375R CYP3A1  细胞色素P450 3A1抗体

hz-5054R CYP4A1  细胞色素P450 4A1抗体

hz-4019R CYP5A1/Thromboxane synthase  血栓素合成酶抗体

hz-5055R CYP4A22  细胞色素P4504A22抗体（脂肪酸Ω羟化酶）

hz-2399R CYP7A1  细胞色素P450 7A1抗体/胆固醇7a羟化酶

hz-2991R CYP2D6  细胞色素P450 2D6抗体

hz-2352R Cytochrome P450 2B6  细胞色素P450 2B6抗体

hz-3853R CYP17  细胞色素P450 17抗体

hz-1292R CYP19/CYP19A1  细胞色素P450 19抗体

hz-5052R CYP7B1  胆固醇25α7羟化酶抗体

hz-3677R CYP8A1/PTGIS  前列环素合成酶抗体

hz-2443R CYP21  胆固醇21-羟化酶抗体

hz-2795R CYP2C19  细胞色素P450 2C19抗体

hz-3899R CYP24A1  细胞色素P450 24A1抗体

hz-5049R CYP27A1  胆固醇27α羟化酶抗体

hz-0461R CYP450  细胞色素P450单氧化酶抗体

hz-5816R RRAGA  RAS相关GTP结合蛋白A抗体

hz-1290R Cyr61/IGFBP10/CCN1  富半胱氨酸肝素结合蛋白61抗体

hz-1725R CYP2E1  细胞色素P450ⅡE1抗体

hz-4562R CYP2E1  细胞色素P450ⅡE1抗体

hz-3900R CYP2R1  细胞色素P450 2R1抗体

hz-5046R CYP46  胆固醇24S－羟化酶

hz-5050R CYP39A1  胆固醇24α7羟化酶抗体

hz-5051R CYP46  胆固醇24羟化酶抗体

hz-5819R TMhz161A  跨膜蛋白161A抗体

hz-0013R Cytochrome C  细胞色素C抗体

hz-5820R USP28  泛素特异性蛋白酶28抗体

hz-3879R p22-phox/Cytochrome b245 Light Chain  细胞色素b245轻链抗体

hz-5821R Desmoglein 2  桥粒芯糖蛋白2抗体

hz-5824R Cadherin like 23  钙粘蛋白23抗体