Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA.
贮存:
储存温度 2-8°C
敏感性:
热敏感
生化和生理学机理:
Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA. Oxaliplatin forms platinum-DNA adducts. Oxaliplatin causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription.