FK19959 | 2-脱氧-D-葡萄糖 | 98% | 1g |
98% | 5g | ||
98% | 25g |
Cas号 | 154-17-6 | MDL: | MFCD00151328 |
Beilstein | 1723331 | EINECS: | --205-823-0 |
分子式 | C6H12O5 | ||
分子量 | 164.16 | ||
别名 | 2-脱氧-D-葡萄糖 ;2-去氧-D-葡萄糖,D-2-脱氧葡萄糖 | ||
分子结构式 | ![]() |
性状 | 溶于水和乙醇。 | ||
贮存 | 储存温度2-8℃ | ||
用途 | 2-脱氧-D-葡萄糖(2-Deoxy-D-Glucose,2-DG)为天然抗代谢物类抗生素,具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。 | ||
生化和生理学机理 | 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK |
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企业名称
上海沪峰化工有限公司
企业信息已认证
企业类型
信用代码
310112000876111
成立日期
2009-03-09
注册资本
50
经营范围
上海易利生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-17号、18-30号第12幢019室
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