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当前位置: 上海基免 > 抗体/抗原 > 芳香烃受体核转录蛋白样2抗体

芳香烃受体核转录蛋白样2抗体

供货周期: 7天
品牌:
型号: 0.2ml/200μg
货号:
报价: ¥1
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产品介绍
芳香烃受体核转录蛋白样2抗体勿使用无霜冷冻箱,因为会冷冻循环,这样会损伤抗体。
英文名称  Anti-ARNTL2/BMAL2 
中文名称  芳香烃受体核转录蛋白样2抗体 
别    名  ARNT L2; ARNTL 2; ARNTL2; ARNTL2 protein; Aryl hydrocarbon receptor nuclear translocator like 2; Aryl hydrocarbon receptor nuclear translocator like protein 2; Aryl hydrocarbon receptor nuclear translocator-like 2; Basic helix loop helix PAS protein MOP9; Basic-helix-loop-helix-PAS protein MOP9; bHLHe6; BMA L2; BMAL 2; BMAL2; Brain and muscle ARNT like 2; Brain and muscle ARNT-like 2; CLIF; CYCLE like factor; CYCLE-like factor; Member of PAS protein 9; MGC124257; MGC149671; MGC149672; MGC158186; MOP 9; MOP9; PASD 9; PASD9; Transcription factor BMAL 2; Transcription factor BMAL2; wu:fj90c09; BMAL2_HUMAN. 
浓    度  1mg/1ml 
规 格  0.2ml/200μg
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Mouse, Rat  
产品类型  一抗    
芳香烃受体核转录蛋白样2抗体研究领域  细胞生物 神经生物学 转录调节因子 表观遗传学  
蛋白分子量  predicted molecular weight: 71kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human ARNTL2 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蜡切片需做抗原修复) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
芳香烃受体核转录蛋白样2抗体产品介绍 BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events.
Function : ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2) is a basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor. ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. It may participate in circadian clock regulation
Subunit : Component of the circadian core oscillator, which includes the CRY proteins, CLOCK, or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with CLOCK to form the ARNTL2-CLOCK transactivator. Can form heterodimers or homodimers which interact directly with CLOCK to form the transcription activator. Also interacts with NPAS2 and HIF1A.
Subcellular Location : Nuclear
Tissue Specificity : Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala. 
Similarity : Contains 1 bHLH (basic helix-loop-helix) domain. 
Contains 1 PAC (PAS-associated C-terminal) domain. 
Contains 2 PAS (PER-ARNT-SIM) domains. 
Database links : UniProtKB/Swiss-Prot: Q8WYA1.2
我们应该如何储存抗体且最大限度地提高保质期,简单地说:
抗体应在(-20℃)中冷冻干燥或浓缩的液体形式,直到需要,避免反复冷冻/解冻周期,降低抗体含量和浓度。相反,冻结在单次使用的等分试样重组抗体或添加防冻剂(甘油或乙二醇),从而使料液可以保持在-20℃下为液体形式,以使移液没有“解冻”。
在4℃下存放,避免抗体(或其他蛋白质溶液)超过几天浓缩存量(> 0.5毫克)通常是稳定的,芳香烃受体核转录蛋白样2抗体微生物添加剂,如叠氮化钠。不要试图保存稀释(<0.1mg/ml时)抗体溶液稳定,除非通过添加“载体”蛋白质或特殊添加剂。
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上海基免实业有限公司

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310116002801941

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2013-03-11

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芳香烃受体核转录蛋白样2抗体由上海基免实业有限公司为您提供,货号,规格:0.2ml/200μg ,CAS号:,如您想了解更多关于芳香烃受体核转录蛋白样2抗体价格、芳香烃受体核转录蛋白样2抗体结构式、批发、用途等信息,欢迎咨询。除供应芳香烃受体核转录蛋白样2抗体外,还可为您提供昆虫蜕皮激素(Ecdysone)检测试剂盒、植物Ca2+-ATP酶(Ca2+-ATPase)检测试剂盒、蘑菇丝氨酸蛋白酶(PRSS)检测试剂盒等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海基免客户服务电话,售前、售后均可联系。
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