腺苷酸环化酶3抗体

英文名称  Anti-ADCY3 

中文名称  腺苷酸环化酶3抗体 

别    名  A cyclase III; AC3; adenylate cyclase 3; Adenylate cyclase type III; ADCY3_HUMAN; Adenylate cyclase type 3; ATP pyrophosphate-lyase 3; AC-III; Adenylate cyclase, olfactive type; AC3.  

浓    度  1mg/1ml 

规 格  0.2ml/200μg   

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit   

产品类型  一抗    

腺苷酸环化酶3抗体研究领域  肿瘤 免疫学 染色质和核信号 信号转导 转录调节因子 
蛋白分子量  predicted molecular weight: 126kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human ADCY3。 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

腺苷酸环化酶3抗体产品介绍 The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones, neurotransmitters and other regulatory molecules. cAMP, in subsequent steps down the signal transduction pathway, can stimulate cAMP-dependent protein kinase A (cPKA), and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways, gene expression, and affect memory functions etc. The stimulation of adenylate cyclases starts with interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins.

Function : Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.

Similarity : Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Contains 2 guanylate cyclase domains.

Database links : UniProtKB/Swiss-Prot: O60266.3