多药耐药相关蛋白5抗体

供货周期：一周

品牌：

规格： 0.2ml/200μg

货号：

CAS号：

报价： ¥1

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产品介绍

多药耐药相关蛋白5抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.

Function : Acts as a multispecific organic anion pump which can transport nucleotide analogs.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : All isoforms are equally expressed in retina.

Similarity : Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.

Contains 2 ABC transmembrane type-1 domains.

Contains 2 ABC transporter domains.

Database links : UniProtKB/Swiss-Prot: O15440.2

英文名称 Anti-MRP5/ABCC5

中文名称 多药耐药相关蛋白5抗体

别名 Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C (CFTR/MRP) member 5; ATP binding cassette sub family C member 5; Canalicular multispecific organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MRP 5; Multi specific organic anion tranporter C; pABC 11; pABC11; SMRP; MRP5_HUMAN.

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域肿瘤细胞生物免疫学细胞凋亡

蛋白分子量 predicted molecular weight: 160kDa

多药耐药相关蛋白5抗体性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human MRP5 N-terminus

亚型 IgG

纯化方法 affinity purified by Protein A