肌肉细胞特异性泛素蛋白连接酶1抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
Subcellular Location : Cytoplasm. Nucleus.
Tissue Specificity : Muscle specific. Selectively expressed in heart and skeletal muscle. Also expressed in the iris.
英文名称 Anti-MuRF1/Trim63
中文名称 肌肉细胞特异性泛素蛋白连接酶1抗体
别 名 MuRF 1; MuRF-1; Muscle-specific RING finger protein 1; Muscle-specific RING finger protein 1; E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; MURF1; MURF 1; MURF2; RNF28; SMRZ; Iris ring finger protein; Muscle specific ring finger protein 2; Ring finger protein 28; RNF28; SMRZ; Striated muscle RING zinc finger protein; TRIM 63; TRIM63; Tripartite motif containing 63; Tripartite motif containing protein 63; Ubiquitin ligase TRIM63.
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit
产品类型 一抗
研究领域 心血管 细胞生物 信号转导
蛋白分子量 predicted molecular weight: 39kDa
肌肉细胞特异性泛素蛋白连接酶1抗体性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human MuRF1 N-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.