效率的因素主要有5个方面：①抗体对抗原的亲合性；②抗体对抗原的特异性；③抗原表位结构在该技术中是如何被改变的；④抗体与抗原结合的易接近性；⑤二级试剂的质量和类型
英文名称 Anti-Ensconsin
中文名称 上皮细胞微管相关蛋白7抗体
别 名 E MAP 115; EMAP115; Epithelial microtubule associated protein of 115 kDa; MAP 7; MAP7; Microtubule associated protein 7; MAP7_HUMAN.
上皮细胞微管相关蛋白7抗体浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Sheep
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 发育生物学 信号转导 干细胞
蛋白分子量 predicted molecular weight: 84kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Ensconsin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Ensconsin is a microtubule associated protein that is predominantly expressed in cells of epithelial origin. Microtubule associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis.
Function : Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.
Subunit : Interacts with TRPV4 (By similarity).
Subcellular Location : Cytoplasm, perinuclear region. Basolateral cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike-like bundles facing intercellular contacts.
Tissue Specificity : Expressed in the skin and cells of epithelial origin. Predominantly expressed in the suprabasal layers of the normal epidermis and relatively abundant in squamous cell carcinomas but barely detectable in basal cell carcinomas.
Post-translational modifications : The association with microtubules is regulated by phosphorylation during the cell cycle. During interphase only phosphorylated on serine. Phosphorylated on threonine in mitosis.
Similarity : Belongs to the MAP7 family.
Database links : UniProtKB/Swiss-Prot: Q14244.1
半个多世纪以来，抗体一直作为常用的研究工具，因此对其使用和储存已有丰富的经验。这些经验让人们知道如何对抗体进行操作，由于抗体的稳定性好，使用并不困难。抗体较其他蛋白不易变性，易于存放、纯化和标记。蛋白G和蛋白A等抗体结合蛋白的发现使得这项工作更具可行性。
选择合适的抗体对免疫化学技术的成功极为重要。没有任何一种来源的抗体能够满足本书所述的各种方法的要求。为了研究某一重要的抗原，应选用具有不同特性的多种抗体。在没有一套良好特性的抗体可用于研究机体中每一种蛋白之前，选择及制备适合各种技术要求的抗体非常必要。
J12214 孕酮(Pg)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Progesterone (Pg) 48T/96T General
J12215 微管关联蛋白2(MAP2)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Microtubule Associated Protein 2 (MAP2) 48T/96T Mus musculus (Mouse)
J12216 血管内皮生长因子受体1(VEGFR1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) 48T/96T Sus scrofa; Porcine (Pig)
J12217 晚期糖基化终末产物受体(AGER)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Advanced Glycosylation End Product Specific Receptor (AGER) 48T/96T Mus musculus (Mouse)
J12218 载脂蛋白M(APOM)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Apolipoprotein M (APOM) 48T/96T Homo sapiens (Human)
J12219 胰岛素样生长因子结合蛋白7(IGFBP7)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Insulin Like Growth Factor Binding Protein 7 (IGFBP7) 48T/96T Homo sapiens (Human)
J12220 α白蛋白(AFM)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Afamin (AFM) 48T/96T Homo sapiens (Human)
J12221 免疫球蛋白M(IgM)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Immunoglobulin M (IgM) 48T/96T Chicken (Gallus)
J12222 脂肪酸合酶(FASN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Fatty Acid Synthase (FASN) 48T/96T Homo sapiens (Human)
J12223 脂肪酸合酶(FASN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Fatty Acid Synthase (FASN) 48T/96T Rattus norvegicus (Rat)
J12224 乳脂球表皮生长因子8(MFGE8)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Milk Fat Globule EGF Factor 8 (MFGE8) 48T/96T Homo sapiens (Human)
J12225 野鼠色基因相关蛋白(AGRP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Agouti Related Protein (AGRP) 48T/96T Rattus norvegicus (Rat)
J12226 激肽释放酶1(KLK1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Kallikrein 1 (KLK1) 48T/96T Rattus norvegicus (Rat)
J12227 胰腺再生蛋白Iα(REG1α)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Regenerating Islet Derived Protein 1 Alpha (REG1a) 48T/96T Rattus norvegicus (Rat)
J12228 胰腺特异转录因子1α(PTF1α)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Pancreas Specific Transcription Factor 1a (PTF1a) 48T/96T Homo sapiens (Human)
J12229 含血管性血友病因子A域蛋白3A(vWA3A)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Von Willebrand Factor A Domain Containing Protein 3A (vWA3A) 48T/96T Mus musculus (Mouse)
J12230 补体因子P(CFP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Complement Factor P (CFP) 48T/96T Homo sapiens (Human)
J12231 肿瘤坏死因子相关凋亡诱导配体(TRAIL)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) 48T/96T Homo sapiens (Human)
J12232 肿瘤坏死因子相关凋亡诱导配体(TRAIL)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) 48T/96T Mus musculus (Mouse)
J12233 核心蛋白聚糖(DCN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Decorin (DCN) 48T/96T Homo sapiens (Human)
J12234 磷脂转运蛋白(PLTP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Phospholipid Transfer Protein (PLTP) 48T/96T Homo sapiens (Human)
J12235 激肽释放酶2(KLK2)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Kallikrein 2 (KLK2) 48T/96T Homo sapiens (Human)
J12236 抗神经节苷脂M1抗体(Anti-GM1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Anti-Ganglioside M1 Antibody (Anti-GM1) 48T/96T Sus scrofa; Porcine (Pig)
J12237 血清淀粉样P物质(SAP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Serum Amyloid P Component (SAP) 48T/96T Mus musculus (Mouse)
J12238 谷胱甘肽S转移酶μ2(GSTμ2)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione S Transferase Mu 2, Muscle (GSTm2) 48T/96T Homo sapiens (Human)
J12239 谷胱甘肽S转移酶α4(GSTα4)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione S Transferase Alpha 4 (GSTa4) 48T/96T Homo sapiens (Human)
J12240 成肌分化蛋白(MyoD)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Myogenic Differentiation (MyoD) 48T/96T Rattus norvegicus (Rat)
J12241 Smad同源物3(Smad3)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) 48T/96T Homo sapiens (Human)
J12242 膜联蛋白A11(ANXA11)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Annexin A11 (ANXA11) 48T/96T Homo sapiens (Human)
J12243 膜联蛋白A1(ANXA1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Annexin A1 (ANXA1) 48T/96T Homo sapiens (Human)
J12244 过氧化还原酶5(PRDX5)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Peroxiredoxin 5 (PRDX5) 48T/96T Homo sapiens (Human)
J12245 氧化低密度脂蛋白(OxLDL)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Oxidized Low Density Lipoprotein (OxLDL) 48T/96T Oryctolagus cuniculus (Rabbit)
J12246 桥粒斑蛋白(DSP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Desmoplakin (DSP) 48T/96T Homo sapiens (Human)
J12247 血管内皮生长因子165(VEGF165)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Vascular Endothelial Growth Factor 165 (VEGF165) 48T/96T Bos taurus; Bovine (Cattle)
J12248 促卵泡素(FSH)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Follicle Stimulating Hormone (FSH) 48T/96T Mus musculus (Mouse)
J12249 胃动蛋白1(GKN1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Gastrokine 1 (GKN1) 48T/96T Homo sapiens (Human)
J12250 α2-巨球蛋白(α2M)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Alpha-2-Macroglobulin (a2M) 48T/96T Rattus norvegicus (Rat)
J12251 纤维胶凝蛋白1(FCN1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Ficolin 1 (FCN1) 48T/96T Homo sapiens (Human)
J12252 甘露聚糖结合凝集素关联丝氨酸蛋白酶2(MASP2)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Mannose Associated Serine Protease 2 (MASP2) 48T/96T Homo sapiens (Human)
J12253 精氨酸(Arg)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Arginine (Arg) 48T/96T General
J12254 末端补体复合体C5b-9(C5b-9)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Terminal Complement Complex C5b-9 (C5b-9) 48T/96T Homo sapiens (Human)
J12255 肿瘤坏死因子相关凋亡诱导配体(TRAIL)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) 48T/96T Canis familiaris; Canine (Dog)
J12256 肿瘤坏死因子相关凋亡诱导配体(TRAIL)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL) 48T/96T Rattus norvegicus (Rat)
J12257 簇集蛋白(CLU)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Clusterin (CLU) 48T/96T Canis familiaris; Canine (Dog)
J12258 胰多肽(PP)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Pancreatic Polypeptide (PP) 48T/96T Mus musculus (Mouse)
J12259 穿孔素1(PRF1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Perforin 1 (PRF1) 48T/96T Rattus norvegicus (Rat)
J12260 α1-抗胰蛋白酶(α1AT)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Alpha-1-Antitrypsin (a1AT) 48T/96T Rattus norvegicus (Rat)
J12261 干扰素γ诱导单核因子(MIγ)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Monokine Induced By Interferon Gamma (MIg) 48T/96T Rattus norvegicus (Rat)
J12262 干扰素诱导T-细胞α亚族趋化剂(ITαC)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Interferon Inducible T-Cell Alpha Chemoattractant (ITaC) 48T/96T Rattus norvegicus (Rat)
J12263 紧密连接蛋白1(TJP1)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Tight Junction Protein 1 (TJP1) 48T/96T Homo sapiens (Human)
J12264 诱导型一氧化氮合酶(NOS2)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) 48T/96T Canis familiaris; Canine (Dog)
J12265 层粘连蛋白(LN)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Laminin (LN) 48T/96T Homo sapiens (Human)
J12266 Endoglin蛋白(ENG)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Endoglin (ENG) 48T/96T Rattus norvegicus (Rat)
J12267 雄激素受体(AR)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Androgen Receptor (AR) 48T/96T Rattus norvegicus (Rat)
J12268 阿黑皮素原(POMC)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Proopiomelanocortin (POMC) 48T/96T Mus musculus (Mouse)
J12269 谷胱甘肽还原酶(GR)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Glutathione Reductase (GR) 48T/96T Rattus norvegicus (Rat)
J12270 内皮素受体A(ETRA)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Endothelin Receptor A (ETRA) 48T/96T Homo sapiens (Human)
J12271 妊娠相关血浆蛋白A2(PAPPA2)上皮细胞微管相关蛋白7抗体检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Pappalysin 2 (PAPPA2) 48T/96T Homo sapiens (Human)
J12272 补体成分5a(C5a)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Complement Component 5a (C5a) 48T/96T Oryctolagus cuniculus (Rabbit)
J12273 乳铁传递蛋白(LTF)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lactoferrin (LTF) 48T/96T Equus caballus; Equine (Horse)
J12274 乳铁传递蛋白(LTF)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lactoferrin (LTF) 48T/96T Canis familiaris; Canine (Dog)
J12275 乳铁传递蛋白(LTF)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Lactoferrin (LTF) 48T/96T Capra hircus; Caprine (Goat)
J12276 髓过氧化物酶(MPO)检测试剂盒(酶联免疫吸附试验法) ELISA Kit for Myeloperoxidase (MPO) 48T/96T Bos taurus; Bovine (Cattle)
更多上皮细胞微管相关蛋白7抗体价格、批发价、品牌、厂家及抗体详细说明书，都可以免费咨询及索取。
关注
已认证
